A young woman's husband apparently commits suicide without warning or reason, leaving behind his wife and infant. Yumiko remarries and moves from Osaka to a small fishing village, yet continues to search for meaning in a lonely world.

Mushi are beings in touch with the essence of life, far more basic and pure than normal living things. Most humans are incapable of perceiving Mushi and are oblivious to their existence, but there are a few who possess the ability to see and interact with Mushi. One such person is Ginko who travels from place to place to research Mushi and aid people suffering from problems caused by them.

To exact revenge, the Liar Game office is revived. The target is only one person - Shinichi Akiyama (Shota Matsuda). Because of new heroine Shinomiya (Mikako Tabe), Shinichi, who kept refusing to take part in the game, finds himself in the game. Along with Akiyama, there's 19 other players competing for the prize of 2 billion yen. Omega (Makiko Esumi), who revived the game, plays the game at the Liar Game office with Alice (Mana Ashida). Alice sets up the game, chooses the players and sets the traps.